The U.S. Department of Agriculture published notice of a final rule that will relax several existing Animal Welfare Act reporting rules. The changes include removing the existing requirement for research facilities to update their registration information at least every three years, removing the existing requirement for the Institutional Animal Care and Use Committee at each facility to conduct a continuing review of research activities involving animals in favor of submission every three years, removing the requirement for research facilities to request inactive status if they no longer use, handle, or transport Animal Welfare Act-regulated animals, and no longer requiring that the Institutional Official or Chief Executive Officer sign the annual report. The rule changes become effective December 27, 2021.